Anything that can cause significant turbidity in a blood sample, such as high leukocyte count or lipemia can potentially interfere with the accuracy of a spectrophotometric hemoglobin assay.

Hematology

Which of the following may interfere with the accurate measurement of hemoglobin:

A. Leukocytosis

B. EDTA

C. Heparin

D. Leukocytosis and lipemia

Beta-thalassemia major, also known as Cooley's anemia, has inherited two genes for beta thalassemia without a normal beta-chain gene. This disease is assoicated with a marked deficiency in beta chain production and in the production of normal Hb A. These patients exhibit increased amounts of iron due to the mutliple transfusions that keep them alive. There is also a striking increase in hemoglobin F and an elevation in hemoglobin A2. Hematology A 5-year-old African American child with hepato-splenomegaly and skeletal abnormalities has the following lab results: WBC = 4,800/cu.mm 20 NRBC/100 WBC RBC = 2.70 X 106 HGB = 6.2 g/dL Many target cells

Marked hypochromasia, anisocytosis and poikilocytosis Serum Iron = 200 μg/dL (elevated) Sickle Solubility = negative

Hemoglobin F = elevated

What is the PROBABLE cause of these findings?

A. Aplastic anemia

B. Beta-thalassemia major

C. Sickle cell anemia

D. Hemoglobin C disease

Which of these advancements in the clinical laboratory has led to concerns about patient privacy

A. high test volumes

B. staffing with several levels of lab professionals

C. computers

D. automated analyzers

hs-CRP is a recent marker of chronic inflammation. New measurements of CRP in lower levels (hs-CRP) are now measured to monitor risk of cardiovascular disease.

Select the statement that best describes hs-CRP?

A. hs-CRP is a measurement of acute inflammation and is used to monitor these conditions

B. hs-CRP is an anti-inflammatory adipokine synthesized by adipocytes

C. hs-CRP is a marker of chronic inflammation and measured to predict the risk of cardiovascular disease

D. hs-CRP is decreased in inflammatory conditions and measured to predict a return of inflammation

A phlebotomist draws an outpatient without wearing gloves. The outpatient displays a badge and cites the laboratory for not following the law. The outpatient is an employee of the:

A. National Fire Protection Association (NFPA)

B. Joint Commission (JC)

C. OSHA D. Centers for Disease Control and Prevention (CDC)